I don't have deep wrinkles yet, but my mother (aged around 58) who has some deep expression lines swears by the new Olay Pro-X products. She is a hard woman to win over in terms of beauty and skin care products and she says she really likes this line of products. Hope this helps!

Thanks for the info.  Is Olay Pro-X a series of products?

I agree with Nortorious that the Olay line is a good one to try, you can read reviews on amazon to get more of an idea.  I have also read that the best place to start is a prescription for retinol, but I find that too harsh.

I got great results from taking a hyaluronic acid supplement...it holds moisture in from the inside out.  Sort of dings out wrinkles like an auto repair shop. Also, since it holds water in, your face feels firm.  Good for eye and joint health, too.  Look for a natural source...I use Neocell.

I haven't had to use anything for deep wrinkles yet either, but I've heard really good feedback about hyaluronic acid. I've also heard that fish oils and oil of primrose oil are helpful.  If you want more specific anti-aging tips, check out our advice section for anti-aging on TotalBeauty.com or this helpful article on great anti-aging skin care ingredients.

Patricia Wexler M.d. Dermatology Intensive Deep Wrinkle Treatment with Mmpi-20 & Retinol

Available at Bath and Body Works